原著論文・総説

2025

1. Yosuke Mizuno, Valérie Panneels, Yuji Furutani*, Gebhard Schertler, Hideki Kandori, Kota Katayama*, “Light-induced FTIR spectroscopy of visual rhodopsin microcrystals grown in lipidic cubic phase”, J. Mol. Biol. 437 (24), 169487, 2025 (DOI: 10.1016/j.jmb.2025.169487)
2. Kyoko Fujita*, Kaho Ishii, Kazune Kobayashi, Yuji Furutani*, Yutaka Takebe, and Eiichi Mizohata*, “Hydrated ionic liquids enhance stability and preserve functionality in transmembrane proteins”, Int. J. Biol. Macromol. 330 (2), 148096, 2025 (DOI: 10.1016/j.ijbiomac.2025.148096)
3. Yuma Ito, Tatsuro Nishikino, Hideki Kandori, and Yuji Furutani*, “The role of retinal chromophore photoisomerization in enhanced inward proton-pumping activity of xenorhodopsin from Nanosalina”, Biochim. Biophys. Acta – Bioenergetics 1866 (3), 149556, 2025 (DOI: 10.1016/j.bbabio.2025.149556)

2024

1. Tatsuki Tanaka, Shoko Hososhima, Yo Yamashita, Teppei Sugimoto, Toshiki Nakamura, Shunta Shigemura, Wataru Iida, Fumiya K. Sano, Kazumasa Oda, Takayuki Uchihashi, Kota Katayama, Yuji Furutani, Satoshi P. Tsunoda, Wataru Shihoya*, Hideki Kandori*, Osamu Nureki*, “The high-light-sensitivity mechanism and optogenetic properties of the bacteriorhodopsin-like channelrhodopsin GtCCR4”, Mol. Cell 84 (18), 3530-3544.e6, 2024 (DOI: 10.1016/j.molcel.2024.08.016)
2. Toshiki Nakamura, Manish Singh, Masahiro Sugiura, Soichiro Kato, Ryo Yamamoto, Hideki Kandori, and Yuji Furutani*, “SNap bond, a crucial hydrogen bond between Ser in helix 3 and Asn in helix 4, regulates the structural dynamics of heliorhodopsin”, J. Mol. Biol. 436 (16), 168666, 2024 (DOI: 10.1016/j.jmb.2024.168666)
3. Èric Catalina-Hernández, Mario López-Martín, David Masnou-Sánchez, Marco Martins, Víctor A. Lórenz-Fonfría, Francesc Jiménez-Altayó, Ute A. Hellmich, Hitoshi Inada, Antonio Alcaraz, Yuji Furutani, Alfons Nonell-Canals, Jose Luis Vázquez-Ibar, Carmen Domene, Rachelle Gaudet, and Alex Perálvarez-Marín*, “Experimental and computational biophysics to identify vasodilator drugs targeted at TRPV2 using agonists based on the probenecid scaffold”, Comput. Struct. Biotechnol. J.,23, 473-482, 2024 (DOI: 10.1016/j.csbj.2023.12.028)

2023

1. Manish Singh, Masanori Hashimoto, Kota Katayama, Yuji Furutani, and Hideki Kandori*, “Internal Proton Transfer in the Activation of Heliorhodopsin”, J. Mol. Biol. 435 (5), 168273, 2023 (DOI: 10.1016/j.jmb.2023.168273)
2. Sahoko Tomida, Akimori Wada and Yuji Furutani*, “Protonation of Asp116 and distortion of an all-trans retinal chromophore in Krokinobacter eikastus rhodopsin 2 causes a redshift in absorption maximum upon dehydration”, Photochem. Photobiol. Sci. 22 (11), 2499-2517, 2023 (DOI: 10.1007/s43630-023-00464-8)
3. Yue Zhao*, Shota Kusama, Yuji Furutani, Wei-Hong Huang, Chih-Wei Luo, and Takao Fuji*, “High-speed scanless entire bandwidth mid-infrared chemical imaging”, Nat. Commun. 14, 3929, 2023 (DOI: 10.1038/s41467-023-39628-6)
4. Shoha Ochiai, Yuki Ichikawa, Sahoko Tomida, and Yuji Furutani*, “Covalent Bond between Lys-255 Residue and the Main Chain is Responsible for Stable Retinal Chromophore Binding and Sodium-Pumping Activity of Krokinobacter Rhodopsin 2”, Biochemistry 62 (12), 1849-1857, 2023 (DOI: 10.1021/acs.biochem.3c00168)
5. Kunisato Kuroi, Takashi Tsukamoto, Naoya Honda, Yuki Sudo*, and Yuji Furutani*, “Concerted primary proton transfer reactions in a thermophilic rhodopsin studied by time-resolved infrared spectroscopy at high temperature”, Biochim. Biophys. Acta – Bioenergetics 1864 (3), 148980, 2023 (DOI: 10.1016/j.bbabio.2023.148980)
6. Masanori Hashimoto, Koichi Miyagawa, Manish Singh, Kota Katayama, Mitsuo Shoji*, Yuji Furutani, Yasuteru Shigeta, and Hideki Kandori*, “Specific Zinc Binding to Heliorhodopsin”, Phys. Chem. Chem. Phys. 25 (4), 3535-3543, 2023 (DOI: 10.1039/d2cp04718g)

2022

1. Masahiro Sugiura, Kazuki Ishikawa, Kota Katayama, Yuji Sumii, Rei Abe-Yoshizumi, Satoshi Tsunoda, Yuji Furutani, Norio Shibata, Leonid Brown, and Hideki Kandori, “Unusual Photoisomerization Pathway in a Near-Infrared Light Absorbing Enzymerhodopsin”, J. Phys. Chem. Lett. 13 (40), 9539–9543, 2022. (DOI: 10.1021/acs.jpclett.2c02334)
2. Andrey Rozenberg, Igor Kaczmarczyk, Donna Matzov, Johannes Vierock, Takashi Nagata, Masahiro Sugiura, Kota Katayama, Yuma Kawasaki, Masae Konno, Yujiro Nagasaka, Mako Aoyama, Ishita Das, Efrat Pahima, Jonathan Church, Suliman Adam, Veniamin A. Borin, Ariel Chazan, Sandra Augustin, Jonas Wietek, Julien Dine, Yoav Peleg, Akira Kawanabe, Yuichiro Fujiwara, Ofer Yizhar, Mordechai Sheves, Igor Schapiro, Yuji Furutani, Hideki Kandori, Keiichi Inoue, Peter Hegemann, Oded Béjà*, Moran Shalev-Benami*, “Rhodopsin-bestrophin fusion proteins from unicellular algae form gigantic pentameric ion channels”, Nat. Struct. Mol. Biol. 29, 592–603, 2022. (DOI: 10.1038/s41594-022-00783-x)

2021

1. Maho Yagi-Utsumi, Kazuhiro Aoki, Hiroki Watanabe, Chihong Song, Seiji Nishimura, Tadashi Satoh, Saeko Yanaka, Christian Ganser, Sae Tanaka, Vincent Schnapka, Ean Wai Goh, Yuji Furutani, Kazuyoshi Murata, Takayuki Uchihashi, Kazuharu Arakawa, and Koichi Kato*, “Desiccation-induced fibrous condensation of CAHS protein from an anhydrobiotic tardigrade”, Sci. Rep. 11:21328, 2021. (DOI: 10.1038/s41598-021-00724-6)
2. Sahoko Tomida, Shinya Kitagawa, Hideki Kandori*, and Yuji Furutani*, “Inverse Hydrogen-Bonding Change Between the Protonated Retinal Schiff Base and Water Molecules upon Photoisomerization in Heliorhodopsin 48C12”, J. Phys. Chem. B 125 (30), 8331-8341, 2021 (DOI: 10.1021/acs.jpcb.1c01907)